These statements have not been evaluated by the Food & Drug Administration. These products are not intended to diagnose, cure or prevent disease.
Xtreme Couture Athletic Pharmaceuticals’ products are completely natural, made from vegetable cultures, and will not produce a positive performance enhancing drug test.
Try to resist the temptation to get overly excited about AA Resveratrol because this substance has been all over the news shows including 60 Minutes.
You may already know that the substance resveratrol is the most promising substance to ever be discovered and researched for it’s Anti-Aging properties. Our product has the most pure and potent form of resveratrol and is combined with quercetin to stay in your body longer.
There is no need for you to triple the recommended amount because you are so excited about the extreme benefits from this product. The recommended dosage is potent as is.You might find that taking AA Resveratrol is the most beneficial thing you will ever take.
Other Key Benefits
January 25, 2009
Mostly for it’s Anti-Aging properties
Resveratrol is a polyphenolic flavonoid found primarily in grape skins and Japanese Knotweed that has multiple health benefits, partially through activation of multiple intracellular pathways mediated by Sirtuin (Sirt) proteins.
“Evidence suggests that activation of SIRT1 leads to multiple metabolic improvements including enhanced glucose utilization, improved insulin sensitivity and increased exercise tolerance”(Wei-jian 2008).
Harvard researcher David Sinclair administered Resveratrol to obese rats consuming a high caloric diet it produced “changes associated with longer lifespan, including increased insulin sensitivity, reduced IGF-1... increased mitochondrial number, and improved motor function”, shifting the physiology toward that of non-obese mice (Sinclair 2006).
Resveratrol beneficially alters blood sugar and lipid metabolism, including increased insulin sensitivity,mitochondrial number, decreased circulating free fatty acids (FFA), and increased lipid metabolism enzymes (PGC-1alpha)(Opie, 2007 ).
A study published in the journal Cell reported that “Treatment of mice with Resveratrol significantly increased their aerobic capacity....and protected mice against diet-induced-obesity and insulin resistance” (Feige 2008).
IA recent paper by Mattson et al found Resveratrol to protect neurons by:
Resveratrol inhibits inflammation through suppression of prostaglandin biosynthesis, intracellular adhesion molecule-1 (ICAM-1), and down regulation of the inflammatory transcription factor NF-k-B (Opie, 2007).
Resveratrol inhibits TNF-ɑ induced endothelial activation and vascular inflammation- a major pathophysiologic feature in the development of vascular aging and atherogenesis (Csiszar 2006).
Through multiple mechanisms listed below, Resveratrol has many ‘vascular protective’ mechanisms (Opie, 2007, Csiszar 2006)
In last 5 years hundreds of studies have been conducted using the phytonutrient Resveratrol, showing it to be beneficial in many applications of glucose regulation, vascular and DNA protection, and enhanced longevity.
It should be noted that subsequent studies have found that trans-Resveratrol (not cis) is the only bioactive form.
Our AAResveratrol is the active trans-resveratrol form.
(Many cheaper products contain the inactive cis-resveratrol)
A high potency, 250 mg capsule
99% standardized extract of trans-Resveratrol (the highest potency available) -most products only contain 20% potency. This means our product is nearly 5 times more potent.
-derived from the roots of Polygonum cuspidatum (Japanese knotweed).
Csiszar. Resveratrol attenuates TNF- -induced activation of coronary arterial endothelial cells: role of NF- B inhibition. AJP: Heart and Circulatory Physiology (2006) vol. 291 (4) pp. H1694-H1699
Feige et al. Specific SIRT1 Activation Mimics Low Energy Levels and Protects against Diet-Induced Metabolic …. Cell Metabolism (2008)
Hall, S. Longevity research. In vino vitalis? Compounds activate life-extending genes. Science, 2003; 301 (5637)
Markus et al. Resveratrol in prevention and treatment of common clinical conditions of aging. Clinical Interventions in Aging (2008)
Mattson et al. VIEWPOINT: MECHANISMS OF ACTION AND THERAPEUTIC POTENTIAL OF NEUROHORMETIC PHYTOCHEMICALS . Dose- Response (2007) vol. 5 pp. 174-186
Sinclair, D. Resveratrol improves health and survival of mice on a high-calorie diet. Nature 444, 337-342. August 2006
Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α. Cell. Volume 127, Issue 6, 15 December 2006, Pages 1109-1122
Opie et al. The red wine hypothesis: from concepts to protective signalling molecules. European Heart Journal (2007) vol. 28 (14) pp. 1683-1693
Wei-jian Jiang. Sirtuins: Novel targets for metabolic disease in drug development. Biochemical and Biophysical ResearchCommunications. Volume 373, Issue 3, 29 August 2008, Pages 341-344